Search results for "metabolic endotoxemia"

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Intestinal microbiota mediates the beneficial effects of n-3 polyunsaturated fatty acids during dietary obesity,

2021

Obesity, now considered as a real worldwide epidemic affecting more than 650 million people, is complex and mainly associated with excessive energy intake and changes in eating habits favoring the consumption of diets rich in saturated fat and sugar. This multifactorial pathology is linked to chronic low grade systemic inflammation. Indeed, a high fat diet (HFD) leads to intestinal microbiota dysbiosis increasing gut permeability (partly attributed to a downregulation of genes encoding tight junction proteins) leading to an increase in bacterial lipopolysaccharides (LPS) levels so-called metabolic endotoxemia. Studies have shown that n-3 polyunsaturated fatty acids (PUFAs) are involved in t…

0301 basic medicinemedicine.medical_specialtydietary obesitySaturated fatlcsh:TP670-699fat-1 miceBiologyGut floraBiochemistry03 medical and health sciences0302 clinical medicineInsulin resistanceInternal medicinemicrobiotamedicinefecal transplantationchemistry.chemical_classificationIntestinal permeabilitymetabolic endotoxemiamedicine.diseasebiology.organism_classificationObesityn-3 polyunsaturated fatty acids030104 developmental biologyEndocrinologychemistry030220 oncology & carcinogenesislcsh:Oils fats and waxesMetabolic syndromeAgronomy and Crop ScienceDysbiosisFood SciencePolyunsaturated fatty acidOCL
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Anthropometric indices, lipid profile, and lipopolysaccharide-binding protein levels in metabolic endotoxemia: A case-control study in Calabar Metrop…

2020

Objectives: To determine the anthropometric indices, lipopolysaccharide-binding proteins (LBP), and lipid profile in patients with metabolic endotoxemia. Methods: The study comprised of 47 patients with metabolic endotoxemia (the metabolic endotoxemia group) and 43 controls (the control group). Patients in the metabolic endotoxemia group were categorized further into three subgroups including the normal weight group (n=8), the overweight group (n=12) and the obese group (n=27). Height, weight, waist, and hip circumference were measured, and waist-hip ratio (WHR) and body mass index (BMI) were calculated. LBP was determined by ELISA and total cholesterol, triglycerides, high density lipoprot…

metabolic endotoxemia; gut; microbiota; lipopolysaccharide-binding protein; body mass index; lipid profile; anthropometric indicesmedicine.medical_specialtyVery low-density lipoproteinWaistmedicine.diagnostic_testbusiness.industrylcsh:Medical emergencies. Critical care. Intensive care. First aidlcsh:RC86-88.9General MedicineOverweightmedicine.diseasechemistry.chemical_compoundEndocrinologyHigh-density lipoproteinchemistryInternal medicineLow-density lipoproteinmedicinelipids (amino acids peptides and proteins)medicine.symptomLipid profilebusinessBody mass indexDyslipidemiaJournal of Acute Disease
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